YMC-Pack PVA-Sil

YMC-Pack PVA-Sil Guard Columns

YMC recommends that you always use a guard column with the same packing material and of the recommended inner diameter for your column. A YMC guard column is normally composed of a cartridge holder and a guard cartridge. The holder can be used repeatedly. Guard cartridges should be changed frequently in order to maximise their protection of the main column.

YMC Pack PVA-Sil, which possesses a polyvinyl alcohol (PVA) surface chemistry, is an excellent alternative to silica gel or other polar bonded normal phases. The polymerised PVA completely covers both external and internal surfaces of the silica support, protecting it against aggressive, high pH buffers and solvents.

In many situations it exhibits better performance characteristics and a unique selectivity and can often resolve compounds that behave poorly on silica. The alcohol functionality present on YMC Pack PVA-Sil is better suited for troublesome compounds, such organic bases, than acidic silanols present in nonbonded silica.